Review of Ethnomedical, Phytochemical and Pharmacological Studies of Zanthoxylum Zanthoxyloids (Lam)

F. Guendéhou, Bruno Agossou Djossa, C. Kènou, C. A. E. Assogbadjo


Zanthoxylum zanthoxyloides (Rutaceae) is a plant commonly used in the treatment of many diseases in tropical areas including digestive disorders, toothache, abdominal pain, sickle cell disease, snake bites, etc. This article reviews phytochemical, pharmacological and toxicological studies of this plant. Many traditional uses of this plant have been validated with nowadays researches. To date, several bioactive compounds, including tannins, saponins, sterols, glycosides, polyterpenes, polyphenols, flavonoids and alkaloids have been isolated from its extracts. These various compounds possess anti-inflammatory and analgesic, antibacterial, anti-sickle cell, antihypertensive, anti-plasmodic, anthelmintic, and insecticidal effects. However, further studies are needed to document the mechanisms of action of these different compounds and their clinical effects.


Traditional medicinal uses; Chemical compounds; Pharmacology, Benin.

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